Searchable abstracts of presentations at key conferences on calcified tissues

ba0003w5.2 | The interactive extracellular matrix | ECTS2014

Collagenous matrix and cell behaviour

Kadler Karl

During the last 12 months we have worked on 2 projects that I will talk about at the ECTS 2014 conference. The first is our work on collagen fibril formation at the cell surface, using tendon as a model tissue. We have shown that the transport of newly-formed fibrils at the plasma membrane requires non-muscle myosin II. The second is that tendon is a peripheral clock tissue. We have shown that the tendons in mice lacking circadian rhythm have abnormal collagen fibril assembly ...